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Antibody & Protein Production and Purification Services
We offer full range of Antibody and Recombinant protein production services. The table below is only a guideline. Please review and contact us for a custom quote for your needs.
| Item# | Description | Time | Cost |
| ARC401 | Antibody or Protein Production in Flask Cultures, 100mL | 2-3 weeks |
$195
|
| ARC402 | Antibody or Protein Production in Roller Bottles, 500mL | 2-3 weeks |
$495
|
| ARC403 | Antibody or Protein Production in Biobags, 500mL (~20-30mg) | 2-3 weeks |
$595
|
| ARC404 | Antibody Production Using Hollow Fiber Bioreactors, 100mg | 3-4 weeks |
$1,995
|
| ARC405 | Antibody Production Using Hollow Fiber Bioreactors, 1000mg | 6-8 weeks |
$5,995
|
| ARC406 | Serum Free and Protein Free Production in Bioreactor, 100mg | 4-5 weeks |
$3,995
|
| ARC407 | Antibody Production Using Bioreactors, 1 - 10grams | >8 weeks |
Call
|
| ARC408 | Endotoxin Free Production Runs | >4 weeks |
Call
|
| ARC409 | Identification & Weaning to Serum & Protein Free Media, Matrix Assay | 3-4 weeks |
$1195
|
| ARC410 | Mouse In Vivo Ascites Production of Antibody, ~100mg | 3-4 weeks |
$895
|
| ARC411 | Mouse In Vivo Ascites Production of Antibody, >100mg | 3-4 weeks |
Call
|
| ARC412 | Protein-A/G Affinity Purification of IgG, up to 100mg | 1-2 weeks |
$595
|
| ARC413 | Protein-A/G Affinity Purification of IgG, up to 1000mg | 1-2 weeks |
$1,595
|
| ARC414 | IgM Purification, ARC Special Process | 1-2 weeks |
Call
|
| ARC415 | Affinity Purification of Tagged Proteins - HIS, HA, GST, Flag | 1-2 weeks |
Call
|
| ARC416 | Peptide Affinity Purification of IgG | 1-2 weeks |
Call
|
| ARC417 | Ammonium Sulfate Concentration (50-100x conc.) | 1-2 weeks |
$195
|
| ARC418 | Ion Exchange Chromatographic Purification | 1-2 weeks |
Call
|
| ARC419 | Superdex / Sephacryl Gel Filtration Purification | 1-2 weeks |
Call
|
| ARC420 | cGMP Bulk Antibody & Protein Production & Purification | > 4 weeks |
Cal
|
The choice of production method should depend on various parameters such as amount needed, cost, and end use of the product.
Scale of production can range from few mg in standard flask or biobags to grams in bioreactors.
Quality of production can range from standard low IgG serum containing production to serum & protein free production to endotoxin free production.
Cost of production will depend on scale and quality of production.
The table below gives an outline of different methods of production, scale and approximate cost (cost estimate does not include purification cost, optimization cell line, selection and screening for best serum or protein free media). We have extensive experience with various methods of production. In addition to in vitro production we also offer in vivo mouse ascites production (although we do not recommend it). Please review the information and contact us to get a custom quote to meet your needs. We guarantee we offer the best service and pricing.
| Method of Production |
Standard Production
Low IgG Serum Media
|
Serum Free Production
Serum & Protein Free Media
|
| T Flasks | 0.5 - 2 mg Cost ~$300 |
0.5 - 2 mg Cost ~$400 |
| Biobags | 10 – 50 mg Cost ~$600 |
10 – 50 mg Cost ~$800 |
| Roller Bottles | 10 – 50 mg Cost ~$600 |
10 – 50 mg Cost ~$800 |
| Spinner Flasks | 10 – 100 mg Cost ~$500 |
10 – 100 mg Cost ~$600 |
| Hollow Fiber Bioreactor | 100 – 5000 mg Starts at ~$2000 |
100 – 5000 mg Starts at ~$3000 |
| Tank Bioreactor | >1 gram Starts at ~$5000 |
>1 gram Starts at ~$8000 |
Check out our cell line services information page to find more information about cell line optimization, clonality testing, productivity testing, cell line rescue services, matrix assay for selection of best serum free and protein free media for growth and productivity from over a choice 20 different medias.
We offer full range of standard and custom procedures for concentrating and purifying proteins and antibodies. These includes Tangential Flow Filtration (TFF), Ammonium Sulfate Precipitation, Protein-A/G, Anti-light chain specific affinity column, Thiophilic purification, Antigen Specific Purification, Tag Specific Purification, Ion Exchange, Gel Filtration, etc. These are techniques which will be chosen to meet your specific situation.
For QC/QA validation of final product we do choose a range of techniques such as SDS-PAGE, Bradford, A280, Western, etc.
This e-mail address is being protected from spambots. You need JavaScript enabled to view it to discuss your project needs.
